Artery Research
Volume 2, Issue 4 , Pages 132-137, November 2008

New insights into cardiovascular risk from the exercise central waveform

  • James E. Sharman

      Affiliations

    • The University of Queensland, Department of Medicine, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, Queensland 4102, Australia
    • The University of Queensland, School of Human Movement Studies, Brisbane, Queensland, Australia
    • Corresponding Author InformationThe University of Queensland, Department of Medicine, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, Queensland 4102, Australia. Tel.: +61 7 3240 6438; fax: +61 7 3240 5399.
    • Grants: Dr. Sharman is supported by an NHMRC Australian Clinical Research Fellowship (reference 409940). Some of the work presented was supported in part from a project grant (G05B 2041) from the National Heart Foundation, Melbourne, Australia.

Received 15 August 2008; accepted 15 September 2008. published online 20 October 2008.

Summary 

Numerous studies in healthy individuals with normal office blood pressure (BP) have shown that a hypertensive response to exercise predicts the future onset of hypertension, as well as cardiovascular morbidity and mortality, independent of office BP. The mechanisms underlying the predictive value of exercise BP are incompletely understood. However, it has been proposed that the additional cardiovascular stress imposed by exercise may unmask the presence of concealed hypertension. A new non-invasive method of exercise arterial pressure waveform analysis (and central BP estimation) may provide additional clinical information, as well as insight into mechanisms, beyond the BP obtained by traditional upper arm cuff methods.

Keywords: Exercise, Tonometry, Augmentation index, Central haemodynamics

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PII: S1872-9312(08)00502-4

doi:10.1016/j.artres.2008.09.001

Artery Research
Volume 2, Issue 4 , Pages 132-137, November 2008