Artery Research
Volume 3, Issue 4 , Pages 132-136 , December 2009

Arterial calcification and its physiological consequences: Ideas from animal models

References 

  1. Abedin M, Tintut Y, Demer LL. Vascular calcification; mechanisms and clinical ramifications. Arterioscler Thromb Vasc Biol. 2004;24:1161–1170
  2. Atkinson J, Poitevin P, Chillon JM, Lartaud I, Levy B. Vascular Ca overload produced by vitamin D3 plus nicotine diminishes arterial distensibility in rats. Am J Physiol. 1994;266:H540–H547
  3. Atkinson J. Age-related medial elastocalcinosis in arteries: mechanisms, animal models and physiological consequences. J Appl Physiol. 2008;105:1643–1651
  4. Basalyga DM, Simionescu DT, Xiong W, Baxer BT, Starcher BC, Vyavahare NR. Elastin degradation and calcification in an abdominal aorta injury model: role of matrix metalloproteinases. Circulation. 2004;110:3480–3487
  5. Blumenthal HT, Lansing AI, Wheeler PA. Calcification of the media of the human aorta and its relation to intimal arteriosclerosis, ageing and disease. Am J Pathol. 1944;20:665–679
  6. Bobryshev YV, Lord RSA. Detection of vascular dendritic cells and extracellular calcium-binding protein S-100 in foci of calcification in human arteries. Acta Histochem Cytochem. 1995;28:371–380
  7. Bobryshev YV, Lord RSA. S-100 positive cells in human arterial intima and in atherosclerotic lesions. Cardiovasc Res. 1995;29:689–696
  8. Byrom FD, Dodson LF. The causation of acute arterial necrosis in hypertensive disease. J Pathol Bacteriol. 1948;60:357–368
  9. Cantini C, Kieffer P, Corman B, Liminana P, Atkinson J, Lartaud-Idjouadiene I. Aminoguanidine and aortic wall mechanics, structure, and composition in aged rats. Hypertension. 2001;38:943–948
  10. Dao HH, Essalihi R, Bouvet C, Moreau P. Evolution and modulation of age-related medial elastocalcinosis: impact on large artery stiffness and isolated systolic hypertension. Cardiovasc Res. 2005;66:307–317
  11. Doherty TM, Fitzpatrick LA, Inoue D, Qiao JH, Fishbein MC, Detrano RC, et al. Molecular, endocrine and genetic mechanisms of arterial calcification. Endocr Rev. 2004;25:629–672
  12. Eisenstein R, Zeruolis L. Vitamin D-induced aortic calcification. Arch Pathol. 1964;77:27–35
  13. Fleckenstein A, Frey M, Zorn J, Fleckenstein G. Calcium, a neglected key factor in hypertension and arteriosclerosis. In:  Laragh JH,  Brenner BM editor. Hypertension: pathophysiology, diagnosis and management. New York: Raven Press; 1990;p. 471–509
  14. Fleisch H, Russell RG, Bisaz S, Muhlbauer R, Williams DA. The inhibitory effect of phosphonates on the formation of calcium phosphate crystals in vitro and on aortic and kidney calcification in vivo. Eur J Clin Invest. 1970;1:12–18
  15. Gaillard V, Casellas D, Seguin-Devaux C, Schohn H, Dauca M, Atkinson J, et al. Piogltazone improves aortic wall elasticity in a rat model of elastocalcinotic arteriosclerosis. Hypertension. 2005;46:1–8
  16. Gaillard V, Jover B, Casellas D, Cordaillat M, Atkinson J, Lartaud I. Renal function and structure in a rat model of arterial calcification and increased pulse pressure. Am J Physiol. 2008;295:222–229
  17. Gertz SD, Kurgan A, Eisenberg D. Aneurysm of the rabbit common carotid artery induced by periarterial application of calcium chloride in vivo. J Clin Invest. 1998;81:649–656
  18. Giummelly P, Colas T, Atkinson J, Robert A, Daly C, Luo D, et al. Fluorescence of the medial aortic elastic lamella in elastocalcinotic rats. N.S. Arch Pharmacol. 1998;358:R218;(abstract)
  19. Greenwald SE. Ageing of the conduit arteries. J Pathol. 2007;211:157–172
  20. Hass GM, Trueheart RE, Taylor CB, Stumpe M. An experimental histologic study of hypervitaminosis D. Am J Pathol. 1958;34:395–431
  21. Henrion D, Chillon JM, Capdeville-Atkinson C, Vinceneux-Feugier M, Atkinson J. Chronic treatment with the angiotensin I converting enzyme inhibitor, perindopril, protects in vitro carbachol-induced vasorelaxation in a rat model of vascular calcium overload. Br J Pharmacol. 1991;104:966–972
  22. Henrion D, Chillon JM, Capdeville-Atkinson C, Atkinson J. Effect of chronic treatment with the calcium entry blocker, isradipine, on vascular calcium overload produced by vitamin D3 and nicotine in rats. J Pharmacol Exp Ther. 1992;260:1–8
  23. Jayalath RW, Mangan SH, Golledge J. Aortic calcification. Eur J Endovasc Surg. 2005;30:476–488
  24. Jegger D, de Silva R, Jeanrenaud X, Nasratullah M, Tevaearai H, van Segesser LK, et al. Ventricular-arterial coupling in a rat model of reduced arterial compliance provoked by hypervitaminosis D and nicotine. Am J Physiol. 2006;291:H1942–H1951
  25. Johnson RC, Leopold JA, Loscalzo J. Vascular calcification. Pathobiological mechanisms and clinical implications. Circ Res. 2006;99:1044–1059
  26. Kieffer P, Robert A, Capdeville-Atkinson C, Atkinson J, Lartaud-Idjouadiene I. Age-related arterial calcification in rats. Life Sci. 2000;66:2371–2381
  27. Lansing AI, Ales M, Rosenthal TB. Calcium and elastin in human arteriosclerosis. J Gerontol. 1949;5:12–19
  28. Lartaud-Idjouadiène I, Lompré AM, Kieffer P, Colas T, Atkinson J. Cardiac consequences of prolonged exposure to an isolated increase in aortic stiffness. Hypertension. 1999;34:63–69
  29. Lehto S, Nuskanen L, Suhonen M, Ronnemaa T, Laakso M. Medial artery calcification. Arterioscler Thromb Vasc Biol. 1996;16:978–983
  30. London GM, Marchais SJ, Safar ME, Genest AF, Guerin AP, Metivier F, et al. Aortic and large artery compliance in end-stage renal failure. Kidney Int. 1990;37:137–142
  31. London GM, Guerin AP, Marchais SJ, Metiver F, Pannier B, Adda H. Arterial media calcification in end-stage renal disease: impact on all-cause and cardiovascular mortality. Nephrol Dial Transplant. 2003;18:1731–1740
  32. Maarek BC, Simon AC, Levenson J, Pithois-Merli I, Bouthier JD. Heterogeneity of the atherosclerotic process in systemic hypertension poorly controlled by drug treatment. Am J Cardiol. 1987;2:1111–1120
  33. Marchais SJ, Boussac I, Guerin AP, Delavaux G, Metivier F, London GM. Arteriosclerosis and antihypertensive response to calcium antagonists in end-stage renal failure. J Cardiovasc Pharmacol. 1991;18(Suppl.):S14–S18
  34. Michel JB, Heudes D, Michel O, Poitevin P, Philippe M, Scalbert E, et al. Effect of chronic ANG I-converting enzyme inhibition on aging processes. II. Large arteries. Am J Physiol. 1994;267:R124–R135
  35. Moe SM, Chen NX. Pathophysiology of vascular calcification in chronic kidney disease. Circ Res. 2004;95:560–567
  36. Moe SM, Chen NX. Inflammation and vascular calcification. Blood Purif. 2005;23:64–71
  37. Mönckeberg JG. Uber die reine mediaverkalkung der extremitatenarterien und ihr verhalten zür arteriosklerose. Virchows Arch (Pathol Anat). 1903;171:141–167
  38. Niederhoffer N, Bobryshev YV, Lartaud-Idjouadiene I, Giummelly P, Atkinson J. Aortic calcification produced by vitamin D3 plus nicotine. J Vasc Res. 1997;34:386–398
  39. Niederhoffer N, Lartaud-Idjouadiene I, Giummelly P, Duvivier C, Peslin R, Atkinson J. Calcification of medial elastic fibres and aortic elasticity. Hypertension. 1997;29:999–1006
  40. Orimo H, Tershita K, Nakamura T, Ohshima J. Ca and atherosclerosis. J Nutr Sci Vitaminol. 1985;31(Suppl.):S33–S36
  41. O'Rourke MF. Pulsatile arterial hemodynamics in hypertension. Aust N Z J Med. 1976;6:40–48
  42. O'Rourke MF, Safar M. Relationship between aortic stiffening and microvascular disease in brain and kidney. Hypertension. 2005;46:200–204
  43. Potokar M, Schmidt-Dunker M. The inhibitory effect of new diphosphonic acids on aortic and kidney calcification in vivo. Atherosclerosis. 1978;30:313–320
  44. Rosenblum IY, Flora L, Eisenstein R. The effect of disodium ethane-1-hydroxy-1,1-disphosphonate (EHDP) on a rabbit model of athero-arteriosclerosis. Atherosclerosis. 1975;22:411–424
  45. Shao JS, Cai J, Towler DA. Molecular mechanisms of vascular calcification – lessons learned from the aorta. Arterioscler Thromb Vasc Biol. 2006;26:1423–1430
  46. Simon A, Levenson J. Early detection of subclinical atherosclerosis in asymptomatic subjects at high risk for cardiovascular disease. Clin Exp Hypertens. 1993;15:1069–1076
  47. Tatchum-Talom R, Niederhoffer N, Amin F, Makki T, Tankosic P, Atkinson J. Aortic stiffness and left ventricular mass in a rat model of isolated systolic hypertension. Hypertension. 1995;26:963–970
  48. Virchow R. Cellular pathology. As based upon physiological and pathological histology. Lecture XVI – atheromatous affection of arteries. 1989 Nutr Rev. 1858;47:23–25
  49. Wilens SL. The post mortem elasticity of the adult aorta. Its relation to age and to distribution of intimal atheromas. Am J Pathol. 1937;13:811–834
  50. Yamauchi-Takihara K, Azuma J, Kishimoto S. Taurine protects against experimental calcinosis in mice. Biochem Biophys Res Commun. 1986;140:679–683

PII: S1872-9312(09)00286-5

doi: 10.1016/j.artres.2009.10.183

Artery Research
Volume 3, Issue 4 , Pages 132-136 , December 2009

Article Tools

* Image Usage & Resolution