Racial differences in relation between carotid and radial augmentation index

Sugawara, Jun; Komine, Hidehiko; Yoshiwaza, Mutsuko; Tarumi, Takashi; Maeda, Seiji; Tanaka, Hirofumi

doi:10.1016/j.artres.2009.12.002

« Previous Next »Artery Research
Volume 4, Issue 1 , Pages 15-18, March 2010

Racial differences in relation between carotid and radial augmentation index☆

Jun Sugawara
- Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan
- Cardiovascular Aging Research Laboratory, Department of Kinesiology and Health Education, University of Texas at Austin, Austin, TX, USA
- Corresponding author. Institute for Human Science and Biomedical Engineering, the National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 6, Tsukuba, Ibaraki 305 8566, Japan. Tel.: +81 29 861 7138; fax: +81 29 861 6660.
Hidehiko Komine
- Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan
Mutsuko Yoshiwaza
- Institute for Human Science and Biomedical Engineering, National Institute of Advanced Industrial Science and Technology, Ibaraki, Japan
- Center for Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki, Japan
- Graduate School of Comprehensive Human Sciences, University of Tsukuba, Tsukuba, Ibaraki, Japan
Takashi Tarumi
- Cardiovascular Aging Research Laboratory, Department of Kinesiology and Health Education, University of Texas at Austin, Austin, TX, USA
Seiji Maeda
- Center for Advanced Research Alliance, University of Tsukuba, Tsukuba, Ibaraki, Japan
Hirofumi Tanaka
- Cardiovascular Aging Research Laboratory, Department of Kinesiology and Health Education, University of Texas at Austin, Austin, TX, USA

Received 29 September 2009; received in revised form 2 November 2009; accepted 2 December 2009. published online 21 January 2010.

Abstract

Background

Augmented central artery wave reflection is a cardiovascular disease risk factor. Augmentation index (AI) obtained from peripheral artery waveforms provides qualitatively similar information to AI from central artery waveforms. Little information is available, however, regarding the influence of racial difference in association between central and peripheral AI.

Methods

We studied 47 White adults (45±17yr, 20 women) and 94 age-matched Asian adults (45±14yr, 42 women).

Results

The White group was significantly taller than the Asian group, whereas there were no significant group differences in blood pressure and heart rate. Carotid and radial AI tended to be lower in White compared with Asian adults (P<0.10 for both). Such tendency disappeared when the difference in height was taken into account using ANCOVA (P=0.84 and P=0.77, respectively). Radial AI was strongly and positively correlated with carotid AI in White adults (r=0.75, P<0.0001) as well as in Asian adults (r=0.82, P<0.0001). The slope and intercept of linear regression line between radial and carotid AI of White adults were highly comparable with those of Asian adults.

Conclusion

AI in the conveniently located peripheral vasculature may provide a surrogate measure of central AI irrespective of difference in race (e.g., Asian vs. White populations).

Keywords: Reflection wave, Applanation tonometry, Race, Central blood pressure