Artery Research
Volume 5, Issue 4 , Pages 122-127 , December 2011

Regulation of arterial stiffness: Cellular, molecular and neurogenic mechanisms

References 

  1. Nichols WW, O'Rourke MF, Vlachopoulos C. McDonald's blood flow in arteries: theoretical, experimental and clinical principles. 6th ed.. London: Hodder Arnold; 2011;
  2. Amery A, Fagard R, Guo C, Staessen J, Thijs L. Isolated systolic hypertension in the elderly: an epidemiologic review. Am J Med. 1991;90(3A):64S–70S
  3. Mattace-Raso FU, van der Cammen TJ, Hofman A, van Popele NM, Bos ML, Schalekamp MA, et al. Arterial stiffness and risk of coronary heart disease and stroke: the Rotterdam Study. Circulation. 2006;113(5):657–663
  4. Franklin SS, Jacobs MJ, Wong ND, L’Italien GJ, Lapuerta P. Predominance of isolated systolic hypertension among middle-aged and elderly US hypertensives: analysis based on National Health and Nutrition Examination Survey (NHANES) III. Hypertension. 2001;37(3):869–874
  5. Franklin SS. Pulse pressure as a risk factor. Clin Exp Hypertens. 2004;26(7–8):645–652
  6. Arnett DK, Evans GW, Riley WA. Arterial stiffness: a new cardiovascular risk factor?. Am J Epidemiol. 1994;140(8):669–682
  7. Blacher J, Guerin AP, Pannier B, Marchais SJ, Safar ME, London GM. Impact of aortic stiffness on survival in end-stage renal disease. Circulation. 1999;99(18):2434–2439
  8. Laurent S, Boutouyrie P, Asmar R, Gautier I, Laloux B, Guize L, et al. Aortic stiffness is an independent predictor of all-cause and cardiovascular mortality in hypertensive patients. Hypertension. 2001;37(5):1236–1241
  9. Wang TJ. Assessing the role of circulating, genetic, and imaging biomarkers in cardiovascular risk prediction. Circulation. 2011;123(5):551–565
  10. Hale JF, McDonald DA, Taylor MG, Womersley JR. The counter chronometer method for recording pulse-wave velocity. J Physiol. 1955;129(1):27–28P
  11. McDonald DA, Taylor MG. An investigation of the arterial system using a hydraulic oscillator. J Physiol. 1956;133(3):74–75P
  12. Hale JF, McDonald DA, Womersley JR. Velocity profiles of oscillating arterial flow, with some calculations of viscous drag and the Reynolds numbers. J Physiol. 1955;128(3):629–640
  13. Resnick N, Gimbrone MA. Hemodynamic forces are complex regulators of endothelial gene expression. FASEB J. 1995;9(10):874–882
  14. Ziegler T, Bouzourene K, Harrison VJ, Brunner HR, Hayoz D. Influence of oscillatory and unidirectional flow environments on the expression of endothelin and nitric oxide synthase in cultured endothelial cells. Arterioscler Thromb Vasc Biol. 1998;18(5):686–692
  15. Santhanam L, Tuday EC, Webb AK, Dowzicky P, Kim JH, Oh YJ, et al. Decreased S-nitrosylation of tissue transglutaminase contributes to age-related increases in vascular stiffness. Circ Res. 2010;107(1):117–125
  16. Intaglietta M, Frangos JA. Introduction: mechanotransduction and translational medicine workshop. J Intern Med. 2006;259(4):336–338
  17. Lehoux S, Castier Y, Tedgui A. Molecular mechanisms of the vascular responses to haemodynamic forces. J Intern Med. 2006;259(4):381–392
  18. Persy V, D’Haese P. Vascular calcification and bone disease: the calcification paradox. Trends Mol Med. 2009;15(9):405–416
  19. Zagura M, Serg M, Kampus P, Zilmer M, Eha J, Unt E, et al. Aortic stiffness and vitamin D are independent markers of aortic calcification in patients with peripheral arterial disease and in healthy subjects. Eur J Vasc Endovasc Surg.
  20. Ng K, Hildreth CM, Phillips JK, Avolio AP. Aortic stiffness is associated with vascular calcification and remodeling in a chronic kidney disease rat model. Am J Physiol Renal Physiol. 2011;300(6):F1431–F1436
  21. Furchgott RF, Cherry PD, Zawadzki JV, Jothianandan D. Endothelial cells as mediators of vasodilation of arteries. J Cardiovasc Pharmacol. 1984;6(Suppl. 2):S336–S343
  22. Van Eyk JE. Overview: the maturing of proteomics in cardiovascular research. Circ Res. 2011;108(4):490–498
  23. Lima B, Forrester MT, Hess DT, Stamler JS. S-nitrosylation in cardiovascular signaling. Circ Res. 2010;106(4):633–646
  24. Kots AY, Martin E, Sharina IG, Murad F. A short history of cGMP, guanylyl cyclases, and cGMP-dependent protein kinases. Handb Exp Pharmacol. 2009;191:1–14
  25. Murad F. Cyclic guanosine monophosphate as a mediator of vasodilation. J Clin Invest. 1986;78(1):1–5
  26. Lai TS, Hausladen A, Slaughter TF, Eu JP, Stamler JS, Greenberg CS. Calcium regulates S-nitrosylation, denitrosylation, and activity of tissue transglutaminase. Biochemistry. 2001;40(16):4904–4910
  27. Mehta K, Fok JY, Mangala LS. Tissue transglutaminase: from biological glue to cell survival cues. Front Biosci. 2006;11:173–185
  28. Iismaa SE, Mearns BM, Lorand L, Graham RM. Transglutaminases and disease: lessons from genetically engineered mouse models and inherited disorders. Physiol Rev. 2009;89(3):991–1023
  29. Lorand L, Graham RM. Transglutaminases: crosslinking enzymes with pleiotropic functions. Nat Rev Mol Cell Biol. 2003;4(2):140–156
  30. Santhanam L, Gucek M, Brown TR, Mansharamani M, Ryoo S, Lemmon CA, et al. Selective fluorescent labeling of S-nitrosothiols (S-FLOS): a novel method for studying S-nitrosation. Nitric Oxide. 2008;19(3):295–302
  31. Kim JH, Bugaj LJ, Oh YJ, Bivalacqua TJ, Ryoo S, Soucy KG, et al. Arginase inhibition restores NOS coupling and reverses endothelial dysfunction and vascular stiffness in old rats. J Appl Physiol. 2009;107(4):1249–1257
  32. Peng X, Haldar S, Deshpande S, Irani K, Kass DA. Wall stiffness suppresses Akt/eNOS and cytoprotection in pulse-perfused endothelium. Hypertension. 2003;41(2):378–381
  33. Barra JG, Armentano RL, Levenson J, Fischer EI, Pichel RH, Simon A. Assessment of smooth muscle contribution to descending thoracic aortic elastic mechanics in conscious dogs. Circ Res. 1993;73(6):1040–1050
  34. Armentano RL, Barra JG, Santana DB, Pessana FM, Graf S, Craiem D, et al. Smart damping modulation of carotid wall energetics in human hypertension: effects of angiotensin-converting enzyme inhibition. Hypertension. 2006;47(3):384–390
  35. Dobrin PB. Mechanical properties of arterises. Physiol Rev. 1978;58(2):397–460
  36. Dobrin PB, Rovick AA. Influence of vascular smooth muscle on contractile mechanics and elasticity of arteries. Am J Physiol. 1969;217(6):1644–1651
  37. Niederhoffer N, Lartaud-Idjouadiene I, Giummelly P, Duvivier C, Peslin R, Atkinson J. Calcification of medial elastic fibers and aortic elasticity. Hypertension. 1997;29(4):999–1006
  38. Johnson RC, Leopold JA, Loscalzo J. Vascular calcification: pathobiological mechanisms and clinical implications. Circ Res. 2006;99(10):1044–1059
  39. London GM, Marchais SJ, Guerin AP, Metivier F. Impairment of arterial function in chronic renal disease: prognostic impact and therapeutic approach. Nephrol Dial Transplant. 2002;17(Suppl. 11):13–15
  40. Johnson KA, Polewski M, Terkeltaub RA. Transglutaminase 2 is central to induction of the arterial calcification program by smooth muscle cells. Circ Res. 2008;102(5):529–537
  41. Vanbavel E, Bakker EN. A vascular bone collector: arterial calcification requires tissue-type transglutaminase. Circ Res. 2008;102(5):507–509
  42. Gow B. The influence of vascular smooth muscle on the viscoelastic properties of blood vessels. In:  DH B editors. Cardiovascular fluid dynamics. 2nd ed. London: Academic Press; 1972;p. 65–110
  43. Lantelme P, Mestre C, Lievre M, Gressard A, Milon H. Heart rate: an important confounder of pulse wave velocity assessment. Hypertension. 2002;39(6):1083–1087
  44. Avolio A, Benetos A. Heart rate, pulse pressure and arterial stiffness. In:  Safar M,  MF OR editor. Handbook of hypertension: arterial stiffness, end-organ damage and cardiovascular prevention. Springer; 2006;
  45. Wolinsky H, Glagov S. A lamellar unit of aortic medial structure and function in mammals. Circ Res. 1967;20(1):99–111
  46. Korner P. Essential hypertension and it’s causes: neural and non-neural mechanisms. Oxford University Press; 2007;
  47. Pieper HP, Paul LT. Responses of aortic smooth muscle studied in intact dogs. Am J Physiol. 1969;217(1):154–160
  48. Nichols WW, McDonald DA. Wave–velocity in the proximal aorta. Med Biol Eng. 1972;10(3):327–335
  49. Pagani M, Schwartz PJ, Bishop VS, Malliani A. Reflex sympathetic changes in aortic diastolic pressure–diameter relationship. Am J Physiol. 1975;229(2):286–290
  50. Lacolley P, Glaser E, Challande P, Boutouyrie P, Mignot JP, Duriez M, et al. Structural changes and in situ aortic pressure–diameter relationship in long-term chemical-sympathectomized rats. Am J Physiol. 1995;269(2 Pt 2):H407–H416
  51. Mangoni AA, Mircoli L, Giannattasio C, Mancia G, Ferrari AU. Effect of sympathectomy on mechanical properties of common carotid and femoral arteries. Hypertension. 1997;30(5):1085–1088
  52. Swierblewska E, Hering D, Kara T, Kunicka K, Kruszewski P, Bieniaszewski L, et al. An independent relationship between muscle sympathetic nerve activity and pulse wave velocity in normal humans. J Hypertens. 2010;28(5):979–984
  53. Nilsson H, Goldstein M, Nilsson O. Adrenergic innervation and neurogenic response in large and small arteries and veins from the rat. Acta Physiol Scand. 1986;126(1):121–133
  54. Fronek K. Trophic effect of the sympathetic nervous system on vascular smooth muscle. Ann Biomed Eng. 1983;11(6):607–615
  55. McEniery CM, Qasem A, Schmitt M, Avolio AP, Cockcroft JR, Wilkinson IB. Endothelin-1 regulates arterial pulse wave velocity in vivo. J Am Coll Cardiol. 2003;42(11):1975–1981
  56. Wilkinson IB, Qasem A, McEniery CM, Webb DJ, Avolio AP, Cockcroft JR. Nitric oxide regulates local arterial distensibility in vivo. Circulation. 2002;105(2):213–217
  57. Schmitt M, Avolio A, Qasem A, McEniery CM, Butlin M, Wilkinson IB, et al. Basal NO locally modulates human iliac artery function in vivo. Hypertension. 2005;46(1):227–231
  58. Bia D, Armentano R, Pessana F, Zocalo Y, Lluberas S, Avolio AP. Non-symmetrical double-logistic analysis of 24 hour arterial stiffness profile in normotensive and hypertensive subjects. Conf Proc IEEE Eng Med Biol Soc. 2008;2008:809–812
  59. Lacolley P, Challande P, Osborne-Pellegrin M, Regnault V. Genetics and pathophysiology of arterial stiffness. Cardiovascular Res. 2009;81(4):637–648
  60. Mitchell GF, Hwang SJ, Vasan RS, Larson MG, Pencina MJ, Hamburg NM, et al. Arterial stiffness and cardiovascular events: the framingham heart study. Circulation 121(4):505–511.
  61. Chaterji S, Park K, Panitch A. Scaffold-free in vitro arterial mimetics: the importance of smooth muscle–endothelium contact. Tissue Eng Part A. 2010;16(6):1901–1912
  62. Braga VA, Medeiros IA, Ribeiro TP, Franca-Silva MS, Botelho-Ono MS, Guimaraes DD. Angiotensin-II-induced reactive oxygen species along the SFO-PVN-RVLM pathway: implications in neurogenic hypertension. Braz J Med Biol Res. 2011;44(9):871–876

 Presented as the invited McDonald Lecture by Alberto Avolio at the Artery11 Meeting of the Association for Research into Arterial Structure and Physiology, Maison Internationale, Cité Universitaire, Paris, France, 13–15 October, 2011.

PII: S1872-9312(11)00059-7

doi: 10.1016/j.artres.2011.10.002

Artery Research
Volume 5, Issue 4 , Pages 122-127 , December 2011